Difference Between Dissolution and Disintegration | Pharma Knowledge By SD Dissolution and disintegration are the two common processes mainly used in pharmaceutical and chemical industries to break the intermolecular and intra-molecular forces that hold substances together. This attempt is done for quality purposes to improve the solubility and bioavailability of, for instance, pharmaceutical drugs into the blood stream. The article discerns the confusion of the difference between these closely related processes. What is disintegration? To disintegrate a substance involves breaking it into small chunks, particles and molecules. Disintegration is a process with which substances are broken down into tiny fragments to improve their solubility. Compounds are disintegrated in chemical reactions. At times the process of disintegration can integrate with dissolution where a solid substance disintegrates into small pieces while dissolving in a solvent until it forms a uniform solution of th...
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